Public-good content from the Brioche practice — anonymized excerpts, methodology one-pagers, terminology glossary, and source-coverage references. Useful on its own; a window into how an engagement works.
A redacted excerpt from a Regulatory Intelligence Report. Real public NDA citations (eltrombopag NDA 022291, avatrombopag NDA 210238). Watermarked illustrative.
Druggability and disease-linkage assessment on a redacted kinase target in fibrosis. Cited to PDB, OpenTargets, ChEMBL, GWAS Catalog, UniProt. Watermarked illustrative.
A single-page reference on the structure of a Brioche written brief — sections, citation conventions, audit-trail bundle, reviewer signature. The standard format every engagement returns.
The 28+ regulatory and clinical sources Brioche reads, organized by category — regulatory authorities, clinical, targets and chemistry, IP, HTA, corporate filings — with origin tags and refresh cadence.
Working definitions of the terms the practice uses — engagement format names, citation conventions, ALCOA+ pillars, IND-pathway terminology — to keep scoping conversations precise.
The questions Brioche asks before opening an engagement — boundaries, deliverable, audience, confidentiality posture, audit-trail handling. Useful before scoping any third-party intelligence engagement, not just ours.