Each format has a defined scope, a fixed delivery window, a named reviewer, and a written deliverable. Choose the format that fits the question. We will write back what we heard, set the boundaries, and confirm before kickoff.
A focused read of the regulatory pathway for one specific asset, indication, or submission question. Built from the primary FDA, EMA, PMDA record and the precedent it sets on the question you are asking.
Best fit when a team is preparing a submission, choosing a regulatory pathway, or evaluating a recent CRL or label decision in the indication.
A full pre-clinical-to-IND read on a discovery asset — regulatory pathway, competitive landscape, IP space, clinical design lessons, deal precedent. The brief a BD lead would write if they had a research desk on call.
Best fit when a team is evaluating in-license, weighing program continuation, or preparing a Series A pitch on the asset.
Ongoing dedicated coverage of a therapeutic area, a pipeline, or a competitive set. A monthly written read plus on-demand short briefs against the same coverage perimeter. The retainer that replaces a consultancy you keep on call.
Best fit when a team needs persistent coverage that holds context across quarters — a CSO who wants the same desk reading the field every month.
A computational validation package for a putative target. Druggability, disease-target linkage strength, the published failure record on the target, the competitive set already pursuing it, and the IP landscape around it.
Best fit when a team is choosing a target to pursue and wants an independent read before committing chemistry resources.
Computational hit finding for a validated target. Virtual screening, generative chemistry, similarity work, predicted profiles, and a triaged hand-off package ready for experimental validation through your CRO of choice.
Best fit when a team has a validated target and needs a computational hit set to feed an experimental validation campaign.
A computational read of an existing scaffold and a proposed improvement plan. SAR analysis from the available data, suggested modifications for potency, selectivity, ADMET, and PK, with predicted profile of every analog proposed.
Best fit when a team has a hit or scaffold in hand and wants an independent computational read on the next round of analogs before committing synthesis effort.
An independent computational evaluation of someone else's discovery asset. Re-validation of claimed activity, an independent target rationale read, the IP and competitive landscape, and a developability profile — for in-license, investment, or partnership decisions.
Best fit when a team is evaluating an external asset for in-license or investment and wants an independent technical read before signing a term sheet.
A 30-minute scoping call. We write the question back to you in our words, define the boundaries of what is in and out of scope, and confirm the deliverable before kickoff. No engagement opens without this step.
The engagement letter is signed. Source list and analytical plan are posted. The named reviewer is assigned and disclosed. The engagement clock starts.
The written analysis is produced against cited primary sources. The named reviewer signs the brief before it leaves the practice. The full audit trail — sources, retrieval timestamps, reviewer identity — is provided alongside the deliverable.
A working session with the team that has to use the brief. We walk through the analysis, log open questions, and scope any follow-up the engagement surfaced.
If you can describe the question in a paragraph, we can scope an engagement against it.
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